ANA Screen ELISA Kit

ANA Screen ELISA Kit The antinuclear antibody (ANA) screen is a broad serological test used to detect autoantibodies directed against various nuclear antigens. It is a key biomarker in the evaluation of systemic autoimmune diseases, particularly connective tissue disorders such as systemic lupus erythematosus (SLE), Sjögren’s syndrome, scleroderma, and mixed connective tissue disease. The ANA screen typically uses indirect immunofluorescence on HEp-2 cells, which allows visualization of different staining patterns (e.g., homogeneous, speckled, nucleolar) that can suggest specific autoantibody profiles and disease associations. In clinical settings, the ANA screen is often the first-line test in patients with suspected autoimmune conditions due to its high sensitivity for SLE. A positive ANA result, especially at significant titers, supports further testing for specific autoantibodies (e.g., anti-dsDNA, anti-Sm, anti-Ro/SSA) that provide diagnostic and prognostic information. However, because ANA can also be positive in healthy individuals or those with non-autoimmune conditions, it must be interpreted in the context of clinical symptoms. In research, ANA screening is used to investigate autoimmunity mechanisms, identify novel nuclear antigens, and explore patterns of disease development and progression. It also helps stratify patient populations for studies targeting specific autoimmune pathways or therapeutic responses. This ANA Screen ELISA Kit is manufactured in Italy by Diametra. Size Sensitivity Cut-Off Dynamic Range Incubation Time 1 hour 15 minutes Sample Type Serum, Plasma (heparin or EDTA) Storage 2-8°C Alternative Names Antinuclear Antibody, Antinuclear Autoantibody Instructions For Use MSDS   Related products Anti-Cardiolipin IgG ELISA Kit SKU: DKO113 $535.00 Inquire Anti-Phospholipid Screen ELISA Kit SKU: DKO114 $685.00 Inquire Anti Beta2 Glycoprotein-1 SCREEN ELISA Kit SKU: DKO145 $485.00 Inquire Anti CP IgG ELISA Kit SKU: DKO149 $610.00 Inquire