Alpha B Crystallin ELISA Kit

Alpha B Crystallin ELISA Kit Alpha-B Crystallin (CRYAB) is a small heat-shock protein primarily known for its role as a molecular chaperone. It prevents the aggregation of misfolded or denatured proteins under various cellular stress conditions. Highly expressed in tissues such as the lens, heart, skeletal muscle, and nervous system, CRYAB contributes to maintaining cytoskeletal integrity, regulating apoptosis, and modulating inflammatory pathways. Its expression increases in response to oxidative stress, ischemia, and mechanical injury, making it a key marker in stress-responsive biology. In research settings, Alpha-B Crystallin is widely studied for its involvement in protein-folding disorders, neurodegeneration, cancer biology, and cardiac disease. Its anti-apoptotic and cytoprotective properties make it a target for understanding cellular resilience under stress. Researchers use CRYAB expression as an indicator of cellular stress, differentiation states, and myopathy progression, as well as a readout in models of multiple sclerosis, Alzheimer’s disease, and cardiomyopathies. In clinical contexts, altered Alpha-B Crystallin levels have been associated with diverse pathologies, including neurodegenerative diseases, cataracts, cardiomyopathies, and certain cancers (e.g., breast and head-and-neck tumors). In oncology, CRYAB overexpression can correlate with tumor aggressiveness and poor prognosis, giving it potential as a diagnostic or prognostic biomarker. In cardiovascular and neuromuscular disease, detecting CRYAB can support the assessment of tissue injury, stress responses, or inherited myopathies. While not yet a routine clinical test, its expanding relevance in disease mechanisms continues to drive interest in its translational applications. This Alpha B Crystallin ELISA Kit is manufactured in Canada by StressMarq. Size Sensitivity 0.009 ng/mL Dynamic Range 0.352 – 22.5 ng/mL Incubation Time 30 minutes Sample Type Cell Lysates, Tissue, Serum Storage 2-8°C (-20°C components) Alternative Names AACRYA, CRYA2, CRYAB, CTPP2, HSPB5, NY Ren 27 antigen, alpha crystallin B Instructions For Use SDS   Related products Anti-dsDNA IgG ELISA Kit SKU: DKO095 $550.00 Inquire Mouse Lipopolysaccharide Binding Protein (LBP) ELISA Kit SKU: HK205-01 $1,260.00 Inquire Complement C4d ELISA Kit SKU: COMPL C4D RUO $1,220.00 Inquire Mouse C1q ELISA Kit SKU: HK211-01 $1,260.00 Inquire